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SKU: Romycin

Azithromycin Dihydrate USP


Romycin 250 Capsule: Each capsule contains Azithromycin 250 mg as Azithromycin Dihydate USP.

Romycin (Azithromycin) is an azalide antibiotic,a subclass of macrolide antibiotic. It acts by binding with the 50s ribosomal subunit of susceptible microorganisms and thus interfering with microbial protein synthesis. Azithromycin has been shown to be active against most strains of the Gram-positive and Gram-negative microorganisms and in clinical infections of Staphylococcus aureus, Streptococcus  agalactiase , Sterptococcus  pyogenes , Streptococcus pneumoniae ,Hameophilus influenzae , Moraxella catarrhalis, Chlamydia trachomatics etc.About 40% Azithromycin of an oral dose is absorbed. After oral administration, Azithromycin is rapidly absorbed and widely distributed throughout the body.

Indications and usage:
Romycin is indicated for the treatment of patients with infections caused by susceptible organisms _Lower respiratory tract infections – Acute bacterial exacerbation of chronic obstructive pulmonary disease (COPD),Community acquired pneumonia and Otitis media.  Upper  respiratory tract infection_ Acute pharyngitis, tonstillitis. Gastointestinal infection- Cholera, diarrhea Typhoid/ Enteric fevers etc.Skin and skin structure infections –Uncomplicated skin ahd skin structure infections. Sexually transmitted disease– Non-gonococal urethristis and    cervicitis. Mycobacterial infections-For proohylaxis,disseminated Mycobacterium avium complex disease.

Dosage and Administration:
Adults- The recommended dose of Romycin for the treatment of mild to moderate acute bacterial exacerbations of chronic obstructive pulmonary disease (COPD), pneumonia pharyngitis , tonsillitis and uncomplicated skin and skin structure infections is 500 mg on the first day followed by 250 mg once daily on day 2 to 5. In typhoid fever recommended dose is 1g on day first and 500 mg for the next 6 days or 1g once daily for 5 days. For the treatment of genital ulcer disease 1000 mg single dose & in urethritis and cervicitis as single dose 2000 mg Azitjromycin. Children dosage:- In acute otitis media and community-acquired pneumonia of Children above 6 months of age the recommended dose of Azithromycin is 10 mg/kg as single dose on the first day followed by 5 mg/kg on the day 2-5(not exceeding 500 mg/day). The recommended dose the Azithromycin for the treatment of children with pharyngitis/tonsillitis is 12 mg/kg once a day for 5 days (not exceeding 500 mg/day .In typhoid/enteric fever dose is 20 mg/kg once daily for 5 days.      
Azithromycin capsule should be given at least 1 hour  before or 2 hours after a meal and tablets can be taken with or without food.

Because Azithromycin is principally eliminated via the liver , thus caution should be exercised when Azithromycin is administered to patients with impaired hepatic functions.
In pregnancy & Nursing mother;  Azithromycin should be used during pregnancy only if clearly needed. And it is not known whether Azithomycin is excreted in breast milk, so caution shoukd be exercised when it is administrated to a nursing mother.

Store in cool and dry place (below 25 ံ C) and dry place & protect from light. Keep out children’s reach.

Romycin 250 Capsule:Each box contains 8 (2x4)capsules in Alu-Alu blister pack.

Manufactured by
The IBN SINA Pharmaceutical Industry Ltd, Bangladesh.

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